The Impact of Childhood Maltreatment on the Development of Mental Disorders in Adulthood: Links to Depressive and Personality Disorders
DOI:
https://doi.org/10.55892/jrg.v8i18.2228Keywords:
Child Abuse, Mental Health, Depression, Personality DisordersAbstract
Child maltreatment represents a serious public health issue with significant impacts on mental health and the neurobiological development of affected individuals. In this context, the present study aimed to analyze the impacts of childhood maltreatment on the development of mental disorders in adulthood, with a focus on depressive and personality disorders. This is an integrative literature review conducted in six stages. Data were collected from the BVS and PubMed platforms based on predefined inclusion and exclusion criteria, resulting in a final sample of 12 articles. The findings revealed structural changes in brain regions such as the hippocampus, amygdala, and prefrontal cortex, as well as epigenetic modifications, including DNA methylation, which influence stress responses and increase vulnerability to psychiatric disorders. Furthermore, the results indicate that individuals exposed to early abuse present greater resistance to treatment and higher recurrence of depressive episodes. It is hoped that this study will contribute to expanding awareness of the impacts of childhood maltreatment, reinforcing the importance of early interventions and public policies aimed at the protection and monitoring of victims, in order to minimize long-term mental health consequences.
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References
ASSIS, Simone Gonçalves de et al. Impactos da violência na escola: um diálogo com professores. Editora Fiocruz, 2023.
AVERY, Aspen D. et al. Prospective associations between childhood exposure to living with adult alcohol misuse and major depressive disorder in adulthood: the role of child maltreatment. Substance Use & Misuse, v. 58, n. 3, p. 371-379, 2023.
BLIHAR, David et al. A meta-analysis of hippocampal and amygdala volumes in patients diagnosed with dissociative identity disorder. Journal of Trauma & Dissociation, v. 22, n. 3, p. 365-377, 2021.
CLEMENS, Vera et al. Lifespan risks of growing up in a family with mental illness or substance abuse. Scientific Reports, v. 10, p. 15453, 2020.
COMTOIS-CABANA, Maude; BARR, Emily; PROVENÇAL, Nadine; OUELLET-MORIN, Isabelle. Association between child maltreatment and depressive symptoms in emerging adulthood: The mediating and moderating roles of DNA methylation. PLOS ONE, v. 18, n. 1, e0280203, 2023.
SANCHES, Leide C. et al. Violência sexual infantil no Brasil: uma questão de saúde pública. Revista Iberoamericana de Bioética, n. 9, p. 1-13, 2019.
MARTÍNEZ, Pablo et al. Tratamiento de la depresión en adultos con estrés adverso temprano: revisión sistemática de su efecto en síntomas relacionados a trauma, ansiedad, desajuste social y calidad de vida. Revista Médica de Chile, Santiago, v. 149, n. 10, p. 1473-1484, 2021.
ERKOREKA, Leire et al. Attachment anxiety as mediator of the relationship between childhood trauma and personality dysfunction in borderline personality disorder. Clinical Psychology & Psychotherapy, v. 29, n. 2, p. 501-511, 2022.
REIS, Deliane Martins; PRATA, Luana Cristina Gonçalves; PARRA, Cláudia Regina. O impacto da violência intrafamiliar no desenvolvimento psíquico infantil. Psicologia. pt, v. 1, n. 1, p. 1-20, 2018.
SILVA, Flávia Calanda da et al. Os impactos da violência sexual vivida na infância e adolescência em estudantes universitários. Revista de Saúde Pública, São Paulo, v. 54, e57, 2020.
SILVA, Graziela Eliana Costa e; RESENDE, Gabriela de Andrade. Violência sexual contra crianças e adolescentes: uma revisão de literatura pós-Estatuto da Criança e do Adolescente (ECA). Congresso Brasileiro de Assistentes Sociais, v. 16, n. 1, 2019.
VIEIRA, Igor Soares et al. Resilience as a mediator factor in the relationship between childhood trauma and mood disorder: A community sample of young adults. Journal of Affective Disorders, v. 274, p. 48-53, 2020.
WARRIER , V. et al. Gene-environment correlations and causal effects of childhood maltreatmente on physical and mental health: a genetically informed approach. The Lancet Psychiatry, v.8, n. 5, p. 373-386, 2021.
WEISSMAN, D. G. et al. Reduced hippocampal and amygdala volume as a mechanism underlying stress sensitization to depression following childhood trauma. Depression and Anxiety, v. 37, n. 9, p. 916–925, 2020.
ZIMMERMANN, Guilherme dos Santos; SIQUEIRA, Luciola Demery; BOHOMOL, Elena. Aplicação da metodologia Lean Seis Sigma nos cenários de assistência à saúde: revisão integrativa. Revista Brasileira de Enfermagem, v. 73, supl. 5, e20190861, 2020.
