PLANNING AND RATIONAL SYNTHESIS OF TETRAHYDROCHINOLINODIONA CORE DERIVATIVES FOR THE PRODUCTION OF ANTICANCERIGENIC DRUGS
DOI:
https://doi.org/10.5281/zenodo.4623913Keywords:
Biological Activity. Cancer. Human Body. Treatment.Abstract
Today, it is noticeable the different forms of cancer manifestation in the human body and all types of stages presented depending on the type of cancer. For those who have cancer more mildly and have treatment time, there is encouragement, but for those with more aggressive cells, time is worth a life. Receiving the news of being with cancer, today in Brazil, is like receiving a death sentence. It is estimated that in Brazil, according to data from the National Cancer Institute, each year more than 500,000 (five hundred thousand) new cancer cases arise. The search for solutions for the treatment of cancer is essential, so the work in question is involved in the development of a new multicomponent reaction that provides directly, with high conversion, in a single reaction step compounds with biological activity. The compounds will be designed to have anti-cancer activities, for which their entire structure will be designed based on substituting groups that are present in molecules in the literature that have proven activity.
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