Prevention and monitoring of anthracycline-induced cardiotoxicity in breast cancer patients
DOI:
https://doi.org/10.5281/zenodo.7308173Keywords:
antraciclinas, câncer de mama, cardiotoxicidade, prevençãoAbstract
Introduction: Anthracyclines are the most effective chemotherapy drugs for the treatment of breast cancer, but they have cardiotoxic effects. Objective: To investigate methods used to monitor and prevent cardiotoxicity caused by anthracyclines in breast cancer patients. Methods: Integrative literature review carried out through searches in the Biblioteca Virtual de Saúde (BVS). Results: It is recommended to check left ventricular ejection fraction every three months and arterial stiffness until the end of treatment. Ramipril obtained cardioprotective effects during the use of anthracyclines. Lisinopril associated with bisoprolol had good cardioprotective results. The use of statins during treatment reduced hospitalization rates for heart failure. Platycondon grandiplorum prevented cardiotoxicity. As an alternative for replacing common anthracyclines, liposomal anthracyclines are used. Conclusion: There is a need to increase the production of studies on the drugs and monitoring methods that were analyzed.
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Sandamali, J. A. N., Hewawasam, R. P., Fernando, M. A. C. S. S., Jayatilaka, K. A. P. W., Madurawe, R. D., Sathananthan, P. P., Ekanayake, U., & Horadugoda, J. (2020). Anthracycline-induced cardiotoxicity in breast cancer patients from southern sri lanka: An echocardiographic analysis. BioMed Research International, 2020, e1847159. https://doi.org/10.1155/2020/1847159
Varghese, S. S., Eekhoudt, C. R., & Jassal, D. S. (2021). Mechanisms of anthracycline-mediated cardiotoxicity and preventative strategies in women with breast cancer. Molecular and Cellular Biochemistry, 476(8), 3099–3109. https://doi.org/10.1007/s11010-021-04152-y
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Bozza, W. P., Takeda, K., Alterovitz, W.-L., Chou, C.-K., Shen, R.-F., & Zhang, B. (2021). Anthracycline-induced cardiotoxicity: Molecular insights obtained from human-induced pluripotent stem cell-derived cardiomyocytes (Hipsc-cms). The AAPS Journal, 23(2), 44. https://doi.org/10.1208/s12248-021-00576-y
Semeraro, G. C., Lamantia, G., Cipolla, C. M., & Cardinale, D. (2021). How to identify anthracycline-induced cardiotoxicity early and reduce its clinical impact in everyday practice. Kardiologia Polska (Polish Heart Journal), 79(2), 114–122. https://doi.org/10.33963/KP.15782
Araújo, W. C. O. (2020). Recuperação da informação em saúde: Construção, modelos e estratégias. http://www.repositorio.ufc.br/handle/riufc/52993
Słowik, A., Jagielski, P., Potocki, P., Streb, J., Ochenduszko, S., Wysocki, P., Gajos, G., & Konduracka, E. (2020). Anthracycline-induced cardiotoxicity prevention with angiotensin-converting enzyme inhibitor ramipril in women with low-risk breast cancer: Results of a prospective randomized study. Kardiologia Polska, 78(2), 131–137. https://doi.org/10.33963/KP.15163
Saleh, Y., Abdelkarim, O., Herzallah, K., & Abela, G. S. (2021). Anthracycline-induced cardiotoxicity: Mechanisms of action, incidence, risk factors, prevention, and treatment. Heart Failure Reviews, 26(5), 1159–1173. https://doi.org/10.1007/s10741-020-09968-2
Bojan, A., Torok-Vistai, T., & Parvu, A. (2021). Assessment and management of cardiotoxicity in hematologic malignancies. Disease Markers, 2021, 6616265. https://doi.org/10.1155/2021/6616265
Lazăr, D. R., Farcaş, A. D., Blag, C., Neaga, A., Zdrenghea, M. T., Căinap, C., Lazăr, F. L., Stef, A., & Căinap, S. S. (2021). Cardiotoxicity: A major setback in childhood leukemia treatment. Disease Markers, 2021, 8828410. https://doi.org/10.1155/2021/8828410
Gavila, J., Seguí, M. Á., Calvo, L., López, T., Alonso, J. J., Farto, M., & Sánchez-de la Rosa, R. (2017). Evaluation and management of chemotherapy-induced cardiotoxicity in breast cancer: A Delphi study. Clinical and Translational Oncology, 19(1), 91–104. https://doi.org/10.1007/s12094-016-1508-y
Souza, C. A. de, Simões, R., Borges, K. B. G., Oliveira, A. N. de, Zogeib, J. B., Alves, B., Malachias, M. V. B., Drummond-Lage, A. P., & Rezende, B. A. (2018). Arterial stiffness use for early monitoring of cardiovascular adverse events due to anthracycline chemotherapy in breast cancer patients. A pilot study. Arquivos Brasileiros de Cardiologia, 111, 721–728. https://doi.org/10.5935/abc.20180168
Wihandono, A., Azhar, Y., Abdurahman, M., & Hidayat, S. (2021). The role of lisinopril and bisoprolol to prevent anthracycline induced cardiotoxicity in locally advanced breast cancer patients. Asian Pacific Journal of Cancer Prevention: APJCP, 22(9), 2847–2853. https://doi.org/10.31557/APJCP.2021.22.9.2847
Abdel-Qadir, H., Bobrowski, D., Zhou, L., Austin, P. C., Calvillo-Argüelles, O., Amir, E., Lee, D. S., & Thavendiranathan, P. (2021). Statin exposure and risk of heart failure after anthracycline- or trastuzumab-based chemotherapy for early breast cancer: A propensity score‒matched cohort study. Journal of the American Heart Association, 10(2), e018393. https://doi.org/10.1161/JAHA.119.018393
Hao, W., Shi, Y., Qin, Y., Sun, C., Chen, L., Wu, C., Bao, Y., & Liu, S. (2020). Platycodon grandiflorum protects against anthracycline-induced cardiotoxicity in early breast cancer patients. Integrative Cancer Therapies, 19, 1534735420945017. https://doi.org/10.1177/1534735420945017