Amyotrophic lateral sclerosis - ALS: progression of the disease in diagnosed patients
DOI:
https://doi.org/10.5281/zenodo.7199354Keywords:
Esclerose Lateral Amiotrófica, Progressão da Esclerose Lateral Amiotrófica, Enfermagem na Esclerose Lateral Amiotrófica, Terapêutica na ELA, Fatores de risco ELA, Diagnóstico da Esclerose Lateral AmiotróficaAbstract
Objective: Dissert about the progression of Amyotrophic Lateral Sclerosis - ALS in diagnosed patients and discourse about the nurse's role in ALS’s therapy. Methods: The study is about a bibliographic integrative revision, between 2017-2022, through research in the electronic data base of the Scientific Electronic Library Online (Scielo), PubMed, BVS and Lilacs. Results: Twenty-six articles were used in this article, the relation between the content of the article and the theme determined in this article was crucial for the elaboration during the dissertation, by showing the most important information and the conclusion of several authors, divided in six categories: The development of the disease; Risk factors; Diagnosis; Symptomatology and its complications; Therapy; and the nurse’s role in ALS. Conclusion: The study allowed purchase knowledge about the disease, although it is still in constant discovery. The treatment of the pathology occurs through palliative care, planning the interventions according to the patient’s condition, with the objective to provide quality of life for the patient, the patient’s family members and the patients' caregivers. The Riluzol was the most effective medication in the treatment of ALS, increasing the survival and assuaging the symptoms. Beyond that, some risk factors for the development of the disease were pointed out. About the nurse’s role in ALS, it was set that their role is very important during the progression of the disease's course and the pathology’s treatment of the diagnosed patient with ALS.
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Gomes MM, Engelhardt E. Jean-Martin Charcot, pai da neurologia moderna: homenagem, 120 anos após sua morte. Arquivos de Neuro-Psiquiatria [online]. 2013, 71(10):815-817. Disponível em: DOI https://doi.org/10.1590/0004-282X20130128
ABrELA [Internet]. 2018. ABrELA – Associação Brasileira de Esclerose Lateral Amiotrófica; Disponível em: https://www.abrela.org.br/
Linden EJ, Linden D, Bareta GM, Brol AM, Heller P, Traverso MED et al. I. Esclerose Lateral Amiotrófica: Artigo de Atualização. FAAE [Internet]. 13 de maio de 2016. :47-62. Disponível em: https://portalperiodicos.unoesc.edu.br/fisioterapiaemacao/article/view/10241
Salvioni C, Oda AL. Protocolo Clínico para o Tratamento do paciente com Esclerose Lateral Amiotrófica/Doença do Neurônio Motor: Guia Terapêutico [Internet]. São José dos Campos – SP: Pulso Editorial Ltda; 2021. :1-151. ISBN: 978-65-88606-04-9. Disponível em: https://www.abrela.org.br/
O que é a Esclerose Lateral Amiotrófica? [Internet]. online; 2018. Dr. Acary Bulle; Disponível em: https://www.einstein.br/noticias/noticia/o-que-e-ela
Esclerose Lateral Amiotrófica (ELA):O que é ELA - Esclerose Lateral Amiotrófica? [Internet]. Site Ministério da Saúde; 2020. Disponível em: https://www.gov.br/saude/pt-br/assuntos/saude-de-a-a-z/e/esclerose-lateral-amiotrofica-ela-1
Oss AKP, Framil JB. O papel da Enfermagem no Cuidado Paliativo em Pacientes com Esclerose Lateral Amiotrófica (ELA). Esclerose Lateral Amiotrófica/Assistência em Enfermagem/Qualidade de Vida [Internet]. 08 Dez 2021. Disponível em: https://repositorio.faema.edu.br/handle/123456789/3077
Limanaqi F, Biagioni F, Gambardella S, Familiari P, Frati A, Fornai F. Promiscuous Roles of Autophagy and Proteasome in Neurodegenerative Proteinopathies. Int J Mol Sci. 2020 Apr 24; 21(8):3028. doi: 10.3390/ijms21083028. PMID: 32344772; PMCID: PMC7215558. Disponível em: https://pubmed.ncbi.nlm.nih.gov/32344772/
Bhattarai A, Chen Z, Chua P, Talman P, Mathers S, Chapman C, et al. Network diffusion model predicts neurodegeneration in limb-onset Amyotrophic Lateral Sclerosis. PLoS One. 2022 Aug 11; 17(8):e0272736. doi: 10.1371/journal.pone.0272736. PMID: 35951510; PMCID: PMC9371353. Disponível em: https://pubmed.ncbi.nlm.nih.gov/35951510/
Kabiljo R, Iacoangeli A, Al-Chalabi A, Rosenzweig I. Amyotrophic lateral sclerosis and cerebellum. Sci Rep. 2022 Jul 22; 12(1):12586. doi: 10.1038/s41598-022-16772-5. PMID: 35869263; PMCID: PMC9307771. Disponível em: https://pubmed.ncbi.nlm.nih.gov/35869263/
Li Q, Zhu W, Wen X, Zang Z, Da Y, Lu J. Beyond the Motor Cortex: Thalamic Iron Deposition Accounts for Disease Severity in Amyotrophic Lateral Sclerosis. Front Neurol. 2022 Feb 24; 13:791300. doi: 10.3389/fneur.2022.791300. PMID: 35280261; PMCID: PMC8907117. Disponível em: https://www.frontiersin.org/articles/10.3389/fneur.2022.791300/full
Makkonen T, Ruottinen H, Puhto R, Helminen M, Palmio J. Speech deterioration in amyotrophic lateral sclerosis (ALS) after manifestation of bulbar symptoms. Int J Lang Commun Disord. 2018 Mar; 53(2):385-392. doi: 10.1111/1460-6984.12357. Epub 2017 Nov 21. PMID: 29159848. Disponível em: https://onlinelibrary.wiley.com/doi/10.1111/1460-6984.12357
Fávero FM, Voos MC, de Castro I, Caromano FA, Oliveira ASB. Epidemiological and clinical factors impact on the benefit of riluzole in the survival rates of patients with ALS. Arquivos de Neuro-Psiquiatria [online]. 2017. 75(8):515-522. Available from: <https://doi.org/10.1590/0004-282X20170083>. ISSN 1678-4227. https://doi.org/10.1590/0004-282X20170083.
Luchesi KF, Silveira IC. Cuidados paliativos, esclerose lateral amiotrófica e deglutição: estudo de caso. CoDAS [online]. 2018. 30(5):1-6. Disponível em: <https://doi.org/10.1590/2317-1782/20182017215>. Epub 30 Ago 2018. ISSN 2317-1782. https://doi.org/10.1590/2317-1782/20182017215.
Andrew AS, Bradley WG, Peipert D, Butt T, Amoako K, Pioro EP, et al. Risk factors for amyotrophic lateral sclerosis: A regional United States case-control study. Muscle Nerve. 2021 Jan; 63(1):52-59. doi: 10.1002/mus.27085. Epub 2020 Oct 18. PMID: 33006184; PMCID: PMC7821307. Disponível em: https://pubmed.ncbi.nlm.nih.gov/33006184/
Anderson EN, Gochenaur L, Singh A, Grant R, Patel K, Watkins S, et al. Traumatic injury induces stress granule formation and enhances motor dysfunctions in ALS/FTD models. Hum Mol Genet. 2018 Apr 15; 27(8):1366-1381. doi: 10.1093/hmg/ddy047. PMID: 29432563; PMCID: PMC6455923. Disponível em: https://pubmed.ncbi.nlm.nih.gov/29432563/
Lian L, Liu M, Cui L, Guan Y, Liu T, Cui B, et al. Environmental risk factors and amyotrophic lateral sclerosis (ALS): A case-control study of ALS in China. J Clin Neurosci. 2019 Aug; 66:12-18. doi: 10.1016/j.jocn.2019.05.036. Epub 2019 May 30. PMID: 31155341. Disponível em: https://pubmed.ncbi.nlm.nih.gov/31155341/
Peters S, Visser AE, D'Ovidio F, Beghi E, Chiò A, Logroscino G, et al. Associations of Electric Shock and Extremely Low-Frequency Magnetic Field Exposure With the Risk of Amyotrophic Lateral Sclerosis. Am J Epidemiol. 2019 Apr 1; 188(4):796-805. doi: 10.1093/aje/kwy287. PMID: 30649156. Disponível em: https://pubmed.ncbi.nlm.nih.gov/30649156/
Dickerson AS, Hansen J, Specht AJ, Gredal O, Weisskopf MG. Population-based study of amyotrophic lateral sclerosis and occupational lead exposure in Denmark. Occup Environ Med. 2019 Apr; 76(4):208-214. doi: 10.1136/oemed-2018-105469. Epub 2019 Jan 31. PMID: 30705111; PMCID: PMC6433465. Disponível em: https://pubmed.ncbi.nlm.nih.gov/30705111/
Ash PEA, Dhawan U, Boudeau S, Lei S, Carlomagno Y, Knobel M, et al. Heavy Metal Neurotoxicants Induce ALS-Linked TDP-43 Pathology. Toxicol Sci. 2019 Jan 1; 167(1):105-115. doi: 10.1093/toxsci/kfy267. PMID: 30371865; PMCID: PMC6317426. Disponível em: https://pubmed.ncbi.nlm.nih.gov/30371865/
Ralli M, Lambiase A, Artico M, Vincentiis M, Greco A. Amyotrophic Lateral Sclerosis: Autoimmune Pathogenic Mechanisms, Clinical Features, and Therapeutic Perspectives. Isr Med Assoc J. 2019 Jul; 21(7):438-443. PMID: 31507117. Disponível em: https://pubmed.ncbi.nlm.nih.gov/31507117/
Brooks BR. El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. Subcommittee on Motor Neuron Diseases/Amyotrophic Lateral Sclerosis of the World Federation of Neurology Research Group on Neuromuscular Diseases and the El Escorial "Clinical limits of amyotrophic lateral sclerosis" workshop contributors. J Neurol Sci. 1994 Jul; 124 Suppl:96-107. doi: 10.1016/0022-510x(94)90191-0. PMID: 7807156. Disponível em: https://pubmed.ncbi.nlm.nih.gov/7807156/
Maksymowicz S, Libura M, Malarkiewicz P. Overcoming therapeutic nihilism. Breaking bad news of amyotrophic lateral sclerosis—a patient‑centred perspective in rare diseases. Neurol Sci 43 , 4257-4265 (2022). https://doi.org/10.1007/s10072-022-05931-1.
Thomas A, Teplansky KJ, Wisler A, Heitzman D, Austin S, Wang J. Voice onset time in early and late amyotrophic lateral sclerosis. Journal of Speech, Language, and Hearing Research. 2022. 65(7):2586-2593. Available from: https://doi.org/10.1044/2022_JSLHR-21-00632.
Tena A, Clarià F, Solsona F, Povedano M. Detecting Bulbar Involvement in Patients with Amyotrophic Lateral Sclerosis Based on Phonatory and Time-Frequency Features. Sensors . 2022; 22(3):1137. https://doi.org/10.3390/s22031137.
Alencar MA, Silva IMM, Hilário SM, Rangel MFA, Abdo JS, Araújo CM, et al. Quality of life, disability, and clinical variables in amyotrophic lateral sclerosis. Arquivos de Neuro-Psiquiatria [online]. 2022. 80(3):255-261. Available from: <https://doi.org/10.1590/0004-282X-ANP-2021-0201>. Epub 17 Dec 2021. ISSN 1678-4227. https://doi.org/10.1590/0004-282X-ANP-2021-0201.
Prado LGR, Bicalho ICS, Vidigal-Lopes M, Prado VGR, Gomez RS, de Souza LC, et al. Depression and anxiety in a case series of amyotrophic lateral sclerosis: frequency and association with clinical features. Einstein (São Paulo). 2017; 15(1):58-60. doi: 10.1590/S1679-45082017AO3870. PMID: 28444090; PMCID: PMC5433308. Disponível em: https://pubmed.ncbi.nlm.nih.gov/28444090/
Alencar MA, Guedes MCB, Pereira TAL, Rangel MFA, Abdo JC, Souza LC. Functional ambulation decline and factors associated in amyotrophic lateral sclerosis. Fisioterapia em Movimento [online]. 2022, 35:1-10. Available from: <https://doi.org/10.1590/fm.2022.35127>. Epub 15 July 2022. ISSN 1980-5918.
Radbruch L, De Lima L, Knaul F, Wenk R, Ali Z, Bhatnaghar S, et al. Redefining Palliative Care-A New Consensus-Based Definition. J Pain Symptom Manage. 2020 Oct; 60(4):754-764. doi: 10.1016/j.jpainsymman.2020.04.027. Epub 2020 May 6. PMID: 32387576; PMCID: PMC8096724. Disponível em: https://pubmed.ncbi.nlm.nih.gov/32387576/
Zucchi E, Vinceti M, Malagoli C, Fini N, Gessani A, Fasano A, et al. High-frequency motor rehabilitation in amyotrophic lateral sclerosis: a randomized clinical trial. Ann Clin Transl Neurol. 2019 Mar 18; 6(5):893-901. doi: 10.1002/acn3.765. PMID: 31139687; PMCID: PMC6529833. Disponível em: https://onlinelibrary.wiley.com/doi/10.1002/acn3.765
Kalron A, Mahameed I, Weiss I, Rosengarten D, Balmor GR, Heching M, et al. Effects of a 12-week combined aerobic and strength training program in ambulatory patients with amyotrophic lateral sclerosis: a randomized controlled trial. J Neurol. 2021 May; 268(5):1857-1866. doi: 10.1007/s00415-020-10354-z. Epub 2021 Jan 3. PMID: 33388929. Disponível em: https://link.springer.com/article/10.1007/s00415-020-10354-z
Pawlukowska W, Baumert B, Gołąb-Janowska M, Pius-Sadowska E, Litwińska Z, Kotowski M, et al. Articulation recovery in ALS patients after lineage-negative adjuvant cell therapy - preliminary report. Int J Med Sci. 2020 Jul 19; 17(13):1927-1935. doi: 10.7150/ijms.47002. PMID: 32788871; PMCID: PMC7415387. Disponível em: https://pubmed.ncbi.nlm.nih.gov/32788871/
Chandrashekhar S, Hamasaki AC, Clay R, McCalley A, Herbelin L, Pasnoor M, et al. Open-label pilot study of ranolazine for cramps in amyotrophic lateral sclerosis. Muscle Nerve. 2022 Jul; 66(1):71-75. doi: 10.1002/mus.27560. Epub 2022 May 11. PMID: 35466411; PMCID: PMC9197965. Disponível em: https://pubmed.ncbi.nlm.nih.gov/35466411/
Ribeiro ACS, Santana DA, Ayoama EA, Silva SG, Lima RN. Diagnósticos e Intervenções de Enfermagem ao Adulto Acometido por Esclerose Lateral Amiotrófica. Revista Brasileira Interdisciplinar. 2019. 1(4):17-23. Disponível em: https://revistarebis.rebis.com.br/index.php/rebis/article/view/46.