Interaction of Serotonin (5-hydroxytryptamine - 5-HT) in Diverticulitis Disease

Authors

DOI:

https://doi.org/10.55892/jrg.v5i11.458

Keywords:

Serotonin, Diverticulitis disease, Inflammation, Nervous system

Abstract

Introduction: The gastrointestinal tract is involved by a complex system that has paramount importance in daily intestinal homeostasis. The intestine is responsible for the production of serotonin and a low and/or high concentration of this hormone may be the cause of diverticulitis. Objective: To show the hypothesis of serotonin in diverticulitis disease. Methodology: Bibliographic research was carried out to construct this integrative review in the MEDLINE/PubMed (via the National Library of Medicine), ScienceDirect (Elsevier), SCOPUS (Elsevier) and SciELO.ORG databases and Google Scholar. Result: 88 articles were found following the research methods, none of the articles were excluded, then they were divided among the authors, read by complete, remaining 7 for construction of the research, being presented in the table with the main hypothesis of the authors. Conclusion: Due to the lack of research and the delimitations of studies relating serotonin and gastrointestinal diseases, this article showed that it is essential to develop more studies to demonstrate the real relationship of the emergence of this pathology with hormone which as a hypothesis of 5-hydroxytryptamine in the inflammation of diverticulitis.

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Author Biographies

Idonilton da Conceição Fernandes, Universidade Federal do Paraná, UFPR, Brasil

[1] Mestrado em andamento em Ciências Farmacêuticas (Conceito CAPES 5) pela Universidade Federal do Paraná, UFPR, Brasil.

Daniela Regina Buch Leite, Universidade Federal do Paraná, UFPR, Brasil

[2] Doutorado em andamento em Ciências Farmacêuticas (Conceito CAPES 5) pela Universidade Federal do Paraná, UFPR, Brasil.

Josiane de Fatima Gaspari Dias, Universidade Federal do Paraná, UFPR, Brasil

[3] Possui graduação em Farmácia Bioquímica e Indústria, mestrado e doutorado em Ciências Farmacêuticas, pela Universidade Federal do Paraná (UFPR)

Deise Prehs Montrucchio, Universidade Federal do Paraná, UFPR, Brasil

[4] Farmacêutica Bioquímica e Industrial formada pela Universidade Federal do Paraná (1999), mestre em Ciências Farmacêuticas pela Universidade Federal do Paraná (2001), na área de Produtos Naturais e doutora em Farmacologia pela Universidade Federal de Santa Maria (2012).

Vinícius Bednarczuk de Oliveira, Universidade Federal do Paraná, UFPR, Brasil

[5] Graduado em Farmácia com habilitação em Indústria pela Universidade Tuiuti do Paraná (2007). Mestre (2012) e Doutor (2016) em Ciências Farmacêuticas pela Universidade Federal do Paraná.

Luciane Dalarmi, Universidade Federal do Paraná, UFPR, Brasil

[6] Graduação em Farmácia e Bioquímica pela Pontifícia Universidade Católica do Paraná (2001), especialização em Tecnologia e Desenvolvimento de Cosméticos pela Faculdade Positivo (2005), mestrado e doutorado em Ciências Farmacêuticas pela Universidade Federal do Paraná (2012 e 2017)

Verônica Del Gragnano Stasiak Bednarczuk de Oliveira, Universidade Federal do Paraná, UFPR, Brasil

[7] Mestrado em andamento em Ciências Farmacêuticas (Conceito CAPES 5) pela Universidade Federal do Paraná, UFPR, Brasil.

Marilis Dallarmi Miguel, Universidade Federal do Paraná, UFPR, Brasil

[8] Possui graduação em Farmácia, Bioquimica Industrial pela Universidade Federal do Paraná (1989), mestrado em Educação (Didática de Ensino Superior) pela Pontifícia Universidade Católica do Paraná (1996) e Doutorado em Agronomia (Produção Vegetal) pela Universidade Federal do Paraná (2000).

Obdulio Gomes Miguel, Universidade Federal do Paraná, UFPR, Brasil

[9] Possui graduação em Licenciatura e Bacharelado em Química pela Pontifícia Universidade Católica do Paraná (1981), Mestrado em Fisico Química pela Universidade Federal de Santa Catarina (1987) e Doutorado em Química pela Universidade Federal de Santa Catarina (1996).

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Published

2022-12-13

How to Cite

FERNANDES, I. da C.; LEITE, D. R. B.; DIAS, J. de F. G.; MONTRUCCHIO, D. P.; OLIVEIRA, V. B. de; DALARMI, L.; OLIVEIRA, V. D. G. S. B. de; MIGUEL, M. D.; MIGUEL, O. G. Interaction of Serotonin (5-hydroxytryptamine - 5-HT) in Diverticulitis Disease. JRG Journal of Academic Studies, Brasil, São Paulo, v. 5, n. 11, p. 579–589, 2022. DOI: 10.55892/jrg.v5i11.458. Disponível em: https://revistajrg.com/index.php/jrg/article/view/458. Acesso em: 21 nov. 2024.

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Vol. 5 No. 11 (2022): Revista JRG de Estudos Acadêmicos

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Artigos

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https://n2t.net/ark:/57118/JRG.v5i11.458

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