Nutritional aspects of gastric cancer patients and their implications on clinical outcome

Authors

DOI:

https://doi.org/10.5281/zenodo.7570468

Keywords:

“status nutritional” “gastric cancer” “malnutrition”

Abstract

The current literature shows that malnutrition in patients with gastric cancer is present in about 60% of patients, with variations depending on tumor stage, histological type and antineoplastic treatment, directly impacting on various aspects.  This study aims to analyze and understand the nutritional aspects, as well as their impacts/implications on the clinical outcome of patients with gastric cancer.  This is an integrative literature review study, in the period 2017-2022, by means of a survey in electronic databases on the PubMed, SCIELO, and Google Academic platforms. Six articles were selected based on a critical analysis and relevance to the suggested theme, showing the impacts of malnutrition on the clinical outcome of gastric cancer patients. Gastric cancer patients with poor nutritional status have a greater tendency to postoperative complications, higher morbidity and mortality, shorter disease-free survival, lower overall survival and lower quality of life.

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Author Biographies

Millena Irene Gonçalves dos Reis, Escola Superior de Ciências da Saúde, (ESCS), DF, Brasil

[1] Nutricionista formada pela Universidade Federal do Piauí (UFPI).  Residente do Programa Multiprofissional em Atenção ao Câncer pela Escola Superior de Ciências da Saúde (ESCS-DF)

Martiniano Bezerra de Lima, Escola Superior de Ciências da Saúde, (ESCS), DF, Brasil

[2] Graduado(a) Graduação em Nutrição pela Universidade Federal da Paraíba, UFPB. Especialização - Residência multiprofissional em terapia intensiva pela Escola Superior de Ciências da Saúde, ESCS. Especialização - Residência multiprofissional em cancerologia pela Escola de Saúde Pública do Ceará, ESP/CE

Fernanda Cintra Lima, Escola Superior de Ciências da Saúde, (ESCS), DF, Brasil

[3] Possui graduação em Nutrição pela Universidade de Brasília (2000), Pós graduação em: Nutrição Humana e Saúde, Obesidade e Emagrecimento, Nutrição Enteral e Parenteral, Nutrição em Nefrologia, Consultoria Alimentar e Nutricional - Personal Dieter e Educação em Saúde para Preceptores do SUS. É especialista em Terapia Nutricional Perenteral e Enteral pela SBNPE. Desde 2007 é nutricionista do Centro Brasiliense de Nefrologia & Diálise, desde 2006 é nutricionista da SES-DF (preceptora da Residência da ESCS/FEPECS desde 2012 - Residência Uniprofissional em Nutrição e Multlprofissional em Atenção ao Câncer), Coordenadora técnico-administrativa da EMTN-IHB e mestre em Ciências da Saúde pela ESCS-FEPECS.

References

AN, S.; EO, W.; LEE, S. Comparison of the Clinical Value of the Geriatric Nutritional Risk Index and Prognostic Nutritional Index as Determinants of Survival Outcome in Patients with Gastric Cancer. Journal of Cancer, v. 13, n. 12, p. 3348–3357, set. 2022.

BARCHI, L. C. et al. Brazilian gastric cancer association guidelines (Part 1): An update on diagnosis, staging, endoscopic treatment and follow-up. Arquivos Brasileiros de Cirurgia Digestiva, v. 33, n. 3, p. 1–8, mai. 2020.

BRAY, F. et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, v. 68, n. 6, p. 394–424, nov. 2018.

COLLATUZZO, G. et al. Exploring the interactions between Helicobacter pylori (Hp) infection and other risk factors of gastric cancer: A pooled analysis in the Stomach cancer Pooling (StoP) Project. International Journal of Cancer, v. 149, n. 6, p. 1228–1238, set. 2021.

FERLAY, J. et al. Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012. European Journal of Cancer, v. 49, n. 6, p. 1374–1403, abr. 2013.

GUO, Z. Q. et al. Survey and analysis of the nutritional status in hospitalized patients with malignant gastric tumors and its influence on the quality of life. Supportive Care in Cancer, v. 28, n. 1, p. 373–380, jan. 2020.

IDA, S.; KUMAGAI, K.; NUNOBE, S. Current status of perioperative nutritional intervention and exercise in gastric cancer surgery: A review. Annals of Gastroenterological Surgery. v. 6, n. 2, p. 197-203, out. 2022.

INSTITUTO NACIONAL DE CÂNCER JOSÉ ALENCAR GOMES DA SILVA. Dieta, nutrição, atividade física e câncer: uma perspectiva global: um resumo do terceiro relatório de especialistas com uma perspectiva brasileira/ Instituto Nacional de Câncer José Alencar Gomes da Silva. – Rio de Janeiro: INCA, 2020.

INSTITUTO NACIONAL DE CÂNCER JOSÉ ALENCAR GOMES DA SILVA. Estimativa 2020: incidência de câncer no Brasil / Instituto Nacional de Câncer José Alencar Gomes da Silva. – Rio de Janeiro: INCA, 2019.

HORIE, L. M. et al. Diretriz BRASPEN de terapia nutricional no paciente com câncer. Braspen J.v. 34, p. 2–32, 2019.

LI, Y. F. et al. Prognostic value of the nutritional risk screening 2002 scale in metastatic gastric cancer: A large-scale cohort study. Journal of Cancer, v. 10, n. 1, p. 112–119, jan. 2019.

LIU, X. et al. Gastric cancer, nutritional status, and outcome. OncoTargets and Therapy, v. 10, p. 2107–2114, abr. 2017.

MIZUKAMI, T.; PIAO, Y. Role of nutritional care and general guidance for patients with advanced or metastatic gastric cancer. Future Oncology, v. 17, n. 23, p. 3101–3109, ago. 2021

MUSCARITOLI, M.; et al. ESPEN practical guideline: Clinical Nutrition 278 in cancer. Clinical Nutrition, v. 40, n. 5, p. 2898–2913, mai. 2021.

NAGHASHI, S.; SOMI, M. H.; NIKNIAZ, Z. Pretreatment nutritional status is associated with quality of life in patients with gastric cancer: a cross-sectional study from Iran. Supportive Care in Cancer, v. 30, n. 4, p. 3313–3319, abr. 2022.

OH, S. E. et al. Prognostic significance of perioperative nutritional parameters in patients with gastric cancer. Clinical Nutrition, v. 38, n. 2, p. 870–876, abr. 2019.

OSCANOA, T. J.; CIEZA, E. Estado nutricional como predictor de mortalidad en el adulto mayor con cáncer gástrico evaluado en un hospital de referencia. Horizonte Médico (Lima), v. 18, n. 2, p. 6–10, dez. 2018.

PLUMMER, M. et al. Global burden of gastric cancer attributable to pylori. International Journal of Cancer, v. 136, n. 2, p. 487–490, jan. 2015.

QIAN, Y. et al. Preoperative Controlling Nutritional Status (CONUT) score predicts short-term outcomes of patients with gastric cancer after laparoscopy-assisted radical gastrectomy. World Journal of Surgical Oncology, v. 19, n. 1, dez. 2021.

SONG, H. et al. Nutritional Risk Index as a Prognostic Factor Predicts the Clinical Outcomes in Patients With Stage III Gastric Cancer. Frontiers in Oncology, v. 12, mai. 2022.

SUGAWARA, K. et al. Geriatric Nutrition Index Influences Survival Outcomes in Gastric Carcinoma Patients Undergoing Radical Surgery. Journal of Parenteral and Enteral Nutrition, v. 45, n. 5, p. 1042–1051, jul. 2021.

WANG, H. M. et al. Nutritional Status and Related Factors in Patients with Gastric Cancer after Gastrectomy: A Cross-Sectional Study. Nutrients, v. 14, n. 13, jul. 2022.

XIAO, Q. et al. Clinical significance of controlling nutritional status score (CONUT) in evaluating outcome of postoperative patients with gastric cancer. Scientific Reports, v. 12, n. 1, dez. 2022.

XU, L.-B. et al. Impact of malnutrition diagnosed using GLIM criteria on clinical outcomes of patients with gastric cancer. Journal of Parenteral and Enteral Nutrition.v. 46, n. 2,p.385-394, mai. 2021.

ZHAO, X. et al. Association between preoperative nutritional status, inflammation, and intestinal permeability in elderly patients undergoing gastrectomy: A prospective cohort study. Journal of Gastrointestinal Oncology, v. 13, n. 3, p. 997–1006, jun. 2022.

ZHU, X. et al. Controlling Nutritional Status score predict the individualized survival of patients with gastric cancer. Asia Pacific Journal of Clinical Nutrition, v. 30, n. 1, p. 51–59, jun. 2021.

Published

2023-01-25

How to Cite

REIS, M. I. G. dos; LIMA, M. B. de; LIMA, F. C. Nutritional aspects of gastric cancer patients and their implications on clinical outcome. JRG Journal of Academic Studies, Brasil, São Paulo, v. 6, n. 12, p. 77–85, 2023. DOI: 10.5281/zenodo.7570468. Disponível em: https://revistajrg.com/index.php/jrg/article/view/476. Acesso em: 4 dec. 2024.

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