Use of bioactive compunds and probiotics in the nutritional management of patientes with food allergy

Authors

DOI:

https://doi.org/10.55892/jrg.v6i13.729

Keywords:

Food allergy, Probiotic, Bioactive compound

Abstract

Food allergy is a chronic condition that affects an increasing number of people around the world. An allergen-restricted diet is the conventional treatment, but it can be difficult to follow and often limits the intake of important nutrients. Objective. Analyze the most recent scientific evidence available on the use of bioactive compounds and probiotics in the nutritional management of food allergy through an integrative literature review. Methodology. Search for randomized controlled trials, clinical studies or meta-analyses, published in the last 5 years, in any language and that deal with the use of bioactive compounds and probiotics in food allergy in humans. Results. A total of 341 articles were obtained in the search. After applying the search filters, we obtained 27 results that underwent title and abstract reading. Finally, a total of 10 randomized controlled trials, clinical studies or meta-analyses were analyzed, all of which were published in English. Conclusion. Probiotics are recognized for having an immunomodulatory effect and the results from the literature analyzed were almost all positive. Most studies focused on milk protein allergy, therefore, there is a need for additional studies on the use of probiotics for the prevention or treatment of food allergies, especially with other allergenic foods, as the results are promising.

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Author Biographies

Gláucia Almeida Rocha Ciulla, Universidade Paulista

[Lattes] - Graduanda em nutrição pela Universidade Paulista - UNIP.

Antônio José de Rezende, Universidade Paulista

[Lattes] - Doutor em Agronomia (Área de Produção Sustentável) e Mestre em Ciências Agrárias pela Universidade de Brasília-Distrito Federal (UnB). Graduado em Agronomia pela UnB-DF.

References

BASTURK, A. et al. Investigation of the efficacy of Lactobacillus rhamnosus GG in infants with cow's milk protein allergy: a randomised double-blind placebo-controlled trial. Probiotics & Antimicro Prot, v. 12, n. 1, p. 138-143, 2020. DOI:10.1007/s12602-019-9516-1.

BRASIL. Resolução RDC nº 243 de 26 de Julho de 2018. Dispõe sobre os Requisitos sanitários dos suplementos alimentares. Órgão emissor: ANVISA – Agência Nacional De Vigilância Sanitária. Disponível em: < http://antigo.anvisa.gov.br/documents/10181/3898888/rdc_243_2018_.pdf/0e39ed31-1da2-4456-8f4a-afb7a6340c15>. Acesso em: 16 de maio de 2023.

BURGOS, F. et al. Immunomodulation properties of biotics and food allergy in pediatrics. Arch Argent Pediatr, v. 120, n. 4, p. 274-280, 2022.

CARDOSO-SILVA, D. et al. Intestinal barrier function in gluten-related disorders. Nutrients, v. 11, n. 10, p. 2325, 2019. DOI:10.3390/nu11102325.

CIANFERONI, A. Wheat allergy: diagnosis and management. J Asthma Allergy, v. 9, p. 13-25, 2016. DOI:10.2147/JAA.S81550.

CUKROWSKA, B. et al. The effectiveness of probiotic Lactobacillus rhamnosus and Lactobacillus casei Strains in children with atopic dermatitis and cow's milk protein allergy: a multicenter, randomized, double blind, placebo controlled study. Nutrients, v. 13, n. 4, p. 1169, 2021. DOI:10.3390/nu13041169.

DISSANAYAKE, E. et al. Skin care and synbiotics for prevention of atopic dermatitis or food allergy in newborn infants: a 2 × 2 factorial, randomized, non-treatment controlled trial. Int Arch Allergy Immunol, v. 180, n. 3, p. 202-211, 2019. DOI:10.1159/000501636.

FENG, H.; WU, Y. The effectiveness of probiotics in treating food and cow's milk allergies among pediatric age group: a meta-analysis of randomized controlled trials. Iran J Allergy Asthma Immunol, v. 22, n. 2, p. 124-137, 2023. DOI:10.18502/ijaai.v22i2.12674.

JING, W.; LIU, Q.; WANG, W. Bifidobacterium bifidum TMC3115 ameliorates milk protein allergy in by affecting gut microbiota: a randomized double-blind control trial. J Food Biochem, v. 44, n. 11, e13489, 2020. DOI:10.1111/jfbc.13489.

LANZARIN, C. et al. Celiac disease and sensitization to wheat, rye, and barley: should we be concerned? Int Arch Allergy Immunol, v. 182, n. 5, p. 440-446, 2021. DOI: 10.1159/000512108.

MAJSIAK, E. et al. Ige-dependent allergy in patients with celiac disease: a systematic review. Nutrients, v. 15, n. 4, p. 995, 2023. DOI:10.3390/nu15040995.

NOCERINO, R. et al. Dietary treatment with extensively hydrolyzed casein formula containing the probiotic Lactobacillus rhamnosus GG prevents the occurrence of functional gastrointestinal disorders in children with cow's milk allergy. J Pediatr, v. 213, p. 137-142, 2019. DOI:10.1016/j.jpeds.2019.06.004.

NURMATOV, U. et al. Allergen immunotherapy for ige-mediated food allergy: a systematic review and meta-analysis. Allergy, v. 72, n. 8, p. 1133-1147, 2017. DOI: 10.1111/all.13124

PAPARO, L. et al. Randomized controlled trial on the influence of dietary intervention on epigenetic mechanisms in children with cow's milk allergy: the EPICMA study Sci Rep, v. 9, n. 1, p. 2828, 2019. DOI:10.1038/s41598-019-38738-w.

PAPARO, L. et al. Targeting food allergy with probiotics. Adv Exp Med Biol, v. 1125, p. 57-68, 2019. DOI:10.1007/5584_2018_316

PLUMMER, E.L. et al. Postnatal probiotics and allergic disease in very preterm infants: sub-study to the ProPrems randomized trial. Allergy, v. 75, n. 1, p. 127-136, 2020. DOI:10.1111/all.14088.

SORENSEN, K.; et al. Amino acid formula containing synbiotics in infants with cow's milk protein allergy: a systematic review and meta-analysis. Nutrients, v. 13, n. 3, p. 935, 2021. DOI:10.3390/nu13030935.

TAN-LIM, C.; ESTEBAN-IPAC, N. Probiotics as treatment for food allergies among pediatric patients: a meta-analysis. World Allergy Organ J, v. 11, n. 1, p. 25, 2018. DOI:10.1186/s40413-018-0204-5.

VALENTA, R. et al. Food allergies: the basics. Gastroenterology, v. 148, n. 6, ed. 4, p. 1120-1131, 2015. DOI:10.1053/j.gastro.2015.02.006.

YAMAMOTO-HANADA, K. et al. Combination of heat-killed Lactiplantibacillus plantarum YIT 0132 (LP0132) and oral immunotherapy in cow's milk allergy: a randomised controlled trial. Benef Microbes, v. 14, n. 1, p. 17-29, 2023. DOI:10.3920/BM2022.0064.

YU, W.; FREELAND, D.M.H.; NADEAU, K.C. Food allergy: immune mechanisms, diagnosis and immunotherapy. Nat Rev Immunol. v. 16, n. 12, p. 751-765, 2016. DOI: 10.1038/nri.2016.111.

ZIMMERMANN, C.; WAGNER, A. E. Impact of food-derived bioactive compounds on intestinal immunity. Biomolecules, v. 11, n. 12, p. 1901, 2021. DOI: 10.3390/biom11121901.

Published

2023-11-01

How to Cite

CIULLA, G. A. R.; REZENDE, A. J. de. Use of bioactive compunds and probiotics in the nutritional management of patientes with food allergy. JRG Journal of Academic Studies, Brasil, São Paulo, v. 6, n. 13, p. 1560–1568, 2023. DOI: 10.55892/jrg.v6i13.729. Disponível em: https://revistajrg.com/index.php/jrg/article/view/729. Acesso em: 17 may. 2024.

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