Morbidity and mortality due to cholecystitis and biliary cholelithiasis in Brazil, macro-regions and states in the period 2012-2021
DOI:
https://doi.org/10.55892/jrg.v7i14.963Keywords:
Cholecystitis, Cholelithiasis, Epidemiology, Time seriesAbstract
Objectives: to describe the epidemiological profile of morbidity and mortality due to cholecystitis and cholelithiasis in Brazil and its regions, between 2012 and 2021; evaluate the temporal trend of morbidity and mortality due to cholecystitis and cholelithiasis in Brazil and its regions in the same period. Methods: Ecological time series study with open data on mortality and hospital admissions for cholecystitis and cholelithiasis in Brazil. Data were studied in the period 2012-2021, according to region of the country, state and cause of death/hospitalization. Mortality and hospitalization rates were calculated using the IBGE resident population in the locations and years evaluated. The temporal trend was calculated using the JoinPoint model, where the Annual Percentage Variation (APV) was considered growth when positive, decreasing when negative and stationary when not significant (p>0.05). Results: In Brazil, 38,370 deaths from cholecystitis and cholelithiasis were recorded from 2012-2021. The average Brazilian rate was 1.86 deaths/100 thousand and 118.24 hospitalizations/100 thousand. Brazil showed a decrease of 4.9% per year in hospitalizations. The state of Maranhão was the only one to show a growth in hospitalizations of 3.3% per year. In terms of mortality, seven states showed annual growth, with Roraima standing out with an increase of 18.7% per year. In the North, Northeast and South regions, an increase in mortality rates of 1.9%, 2.1% and 1.3% per year, respectively, was identified. Conclusion: In Brazil, high rates of hospital morbidity and mortality due to cholecystitis and cholelithiasis were identified. Regarding the temporal trend, there was an annual reduction in hospital admissions in some states and in all Brazilian macro-regions and mortality increased, especially in the North and Northeast regions.
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BRASIL; CONSELHO NACIONAL DE SAÚDE. Resolução No 510, de 07 de abril de 2016. 2016. Disponível em: http://conselho.saude.gov.br/resolucoes/2016/Reso510.pdf.
CARBONELL, A. M. et al. Do patient or hospital demographics predict cholecystectomy outcomes? A nationwide study of 93,578 patients. Surgical Endoscopy And Other Interventional Techniques, [s. l.], v. 19, n. 6, p. 767–773, 2005.
DUA, Anahita et al. Gender based differences in management and outcomes of cholecystitis. The American Journal of Surgery, [s. l.], v. 206, n. 5, p. 641–646, 2013a.
DUA, Anahita et al. Gender based differences in management and outcomes of cholecystitis. The American Journal of Surgery, [s. l.], v. 206, n. 5, p. 641–646, 2013b.
GALLAHER, Jared R.; CHARLES, Anthony. Acute Cholecystitis: A Review. JAMA, [s. l.], v. 327, n. 10, p. 965–975, 2022.
INSTITUTO BRASILEIRO DE GEOGRAFIA E ESTATÍSTICA. Projeção da população do Brasil e das Unidades da Federação. [S. l.], 2021. Disponível em: https://www.ibge.gov.br/apps/populacao/projecao/index.html. Acesso em: 18 out. 2021.
IRIGONHÊ, Alan Tibério Dalpiaz et al. Análise do perfil clínico epidemiológico dos pacientes submetidos a Colecistectomia Videolaparoscópica em um hospital de ensino de Curitiba. Revista do Colégio Brasileiro de Cirurgiões, [s. l.], v. 47, p. e20202388, 2020.
JUNIOR SCHINDLER, Emerson et al. Abordagem diagnóstica e tratamento da colecistite aguda: uma revisão narrativa | Revista Eletrônica Acervo Saúde. Revista Eletrônica Acervo Saúde, [s. l.], v. 13, n. 9, 2021. Disponível em: https://acervomais.com.br/index.php/saude/article/view/8772. Acesso em: 18 jan. 2024.
KIM, H. J. et al. Permutation tests for joinpoint regression with applications to cancer rates. Statistics in Medicine, [s. l.], v. 19, n. 3, p. 335–351, 2000.
LI, H. Z.; DU, L. B. [Application of Joinpoint regression model in cancer epidemiological time trend analysis]. Zhonghua Yu Fang Yi Xue Za Zhi [Chinese Journal of Preventive Medicine], [s. l.], v. 54, n. 8, p. 908–912, 2020.
MAYA, Maria Cristina et al. Colecistite aguda: diagnóstico e tratamento. Revista Hospital Universitário Pedro Ernesto (TÍTULO NÃO-CORRENTE), [s. l.], v. 8, n. 1, 2009. Disponível em: https://www.e-publicacoes.uerj.br/revistahupe/article/view/9233. Acesso em: 18 jan. 2024.
NUNES, Emeline Caldana; ROSA, Roger dos Santos; BORDIN, Ronaldo. HOSPITALIZATIONS FOR CHOLECYSTITIS AND CHOLELITHIASIS IN THE STATE OF RIO GRANDE DO SUL, BRAZIL. ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo), [s. l.], v. 29, p. 77–80, 2016.
ÖNDER, Akın et al. Gangrenous Cholecystitis: Mortality and Risk Factors. International Surgery, [s. l.], v. 100, n. 2, p. 254–260, 2015.
PEREIRA, Débora Linsbinski et al. Perfil epidemiológico de morbidade por colelitíase e colecistite em Mato Grosso. Revista Ciência e Estudos Acadêmicos de Medicina, [s. l.], n. 12, 2020. Disponível em: https://periodicos.unemat.br/index.php/revistamedicina/article/view/4271. Acesso em: 18 jan. 2024.
SANDBLOM, Gabriel et al. Mortality after a cholecystectomy: a population-based study. HPB, [s. l.], v. 17, n. 3, p. 239–243, 2015.
SANTANA, Júlia Medeiros et al. Colecistopatias e o tratamento das suas complicações: uma revisão sistemática de literatura / Colecistopathies and the treatment of their complications: a systematic review of literature. Brazilian Journal of Health Review, [s. l.], v. 4, n. 1, p. 3597–3606, 2021.
SCHIRMER, Bruce D.; WINTERS, Kathryne L.; EDLICH, Richard. Cholelithiasis and Cholecystitis. Journal of Long-Term Effects of Medical Implants, [s. l.], v. 15, n. 3, 2005. Disponível em: https://www.dl.begellhouse.com/journals/1bef42082d7a0fdf,69622d0e4ea6cf4b,07f88f8255346b09.html. Acesso em: 18 jan. 2024.
SHAFFER, Eldon A. Epidemiology of gallbladder stone disease. Best Practice & Research Clinical Gastroenterology, [s. l.], v. 20, n. 6, Gallstone Disease, p. 981–996, 2006.
STINTON, Laura M.; SHAFFER, Eldon A. Epidemiology of Gallbladder Disease: Cholelithiasis and Cancer. Gut and Liver, [s. l.], v. 6, n. 2, p. 172–187, 2012.
SURVEILLANCE RESEARCH PROGRAM. JoinPoint Regression Program. versão 4.9.0.1. National Cancer Institute: [s. n.], 2022. Statistical Methodology and Applications Branch.
WADHWA, Vaibhav et al. Nationwide trends of hospital admissions for acute cholecystitis in the United States. Gastroenterology Report, [s. l.], v. 5, n. 1, p. 36–42, 2017.
