Alterações neuropsiquiátricas da COVID-19: uma revisão de literatura
DOI:
https://doi.org/10.55892/jrg.v8i18.1942Palabras clave:
COVID-19, Síndrome Pós-COVID-19 aguda, Transtornos Mentais, Doenças do Sistema NervosoResumen
O surgimento recente da COVID-19 associado a sua rápida expansão e acometimentos de caráter sistêmico, leva ao desconhecimento quanto a abrangência de manifestações decorrentes da doença. Assim, a síndrome pós-COVID constitui em diversas sequelas persistentes após o período de infecção pelo SARS-COV-2, as quais ainda não foram completamente elucidadas. Esse estudo, portanto, tem como objetivo revisar na literatura as alterações decorrentes da síndrome pós-COVID no sistema nervoso e também em âmbito psiquiátrico. Dessa forma, transtornos psiquiátricos, alterações de sono, déficits cognitivos, afecções neurovasculares, síndromes relativas ao sistema nervoso central e periférico foram observados nessa condição e descritos nesse estudo. Ademais, caracteriza os fatores de risco relativos ao maior acometimento em determinadas populações, como sexo feminino e doenças crônicas, e maior gravidade da COVID-19, os quais, em geral, possuem relação fisiopatológica a partir da exacerbação do processo inflamatório dessas condições e daquele oriundo da infecção pelo SARS-COV-2. Cabe ressaltar, a importância do aspecto biopsicossocial quando observado o caráter estressor gerado pelo isolamento social e suas consequências.
Descargas
Citas
ALVES, Emily Viega; BEBER, Bárbara Costa. Self-perception of cognitive sequels in post-COVID-19 individuals. Dementia e Neuropsychologia, v. 17, p. 1–8, 2023.
ARIZA, Mar et al. COVID-19 severity is related to poor executive function in people with post-COVID conditions. Journal of Neurology, v. 270, n. 5, p. 2392–2408, 2023.
CHUDZIK, Michał et al. Long-COVID Clinical Features and Risk Factors: A Retrospective Analysis of Patients from the STOP-COVID Registry of the PoLoCOV Study. Viruses, v. 14, n. 8, 2022.
COLLANTES, Maria Epifania V. et al. Neurological Manifestations in COVID-19 Infection: A Systematic Review and Meta-Analysis. Canadian Journal of Neurological Sciences, v. 48, n. 1, p. 66–76, 2021.
DA SILVA JÚNIOR, Ronaldo Teixeira et al. COVID-19 neuropsychiatric repercussions: Current evidence on the subject. World Journal of Methodology, v. 12, n. 5, p. 365–380, 2022.
DAMIANO, Rodolfo Furlan et al. Association between chemosensory impairment with neuropsychiatric morbidity in post-acute COVID-19 syndrome: results from a multidisciplinary cohort study. European Archives of Psychiatry and Clinical Neuroscience, v. 273, n. 2, p. 325–333, 2023.
GRAHAM, Edith L. et al. Persistent neurologic symptoms and cognitive dysfunction in non-hospitalized Covid-19 “long haulers”. Annals of Clinical and Translational Neurology, v. 8, n. 5, p. 1073–1085, 2021.
HE, Xudong et al. Neurological and psychiatric presentations associated with COVID-
European Archives of Psychiatry and Clinical Neuroscience, v. 272, n. 1, p. 41–52, 2022. Disponível em: <https://doi.org/10.1007/s00406-021-01244-0>.
IMOTO, Waki et al. A cross-sectional, multicenter survey of the prevalence and risk factors for Long COVID. Scientific Reports, v. 12, n. 1, p. 1–10, 2022. Disponível em:
<https://doi.org/10.1038/s41598-022-25398-6>.
KREMER, Stéphane et al. Neurologic and neuroimaging findings in patients with COVID-19: A retrospective multicenter study. Neurology, v. 95, n. 13, p. E1868–E1882, 2020.
MOURA, Alissa Elen Formiga et al. Central hypersomnia and chronic insomnia: expanding the spectrum of sleep disorders in long COVID syndrome - a prospective cohort study. BMC Neurology, v. 22, n. 1, p. 1–10, 2022. Disponível em:
<https://doi.org/10.1186/s12883-022-02940-7>.
PERNA, S. et al. A cross-sectional analysis of post-acute COVID-19 symptoms. Annali di Igiene Medicina Preventiva e di Comunita, v. 34, n. 5, p. 478–489, 2022.
RETORNAZ, Frédérique et al. Long-term neuromuscular consequences of SARS-Cov-2 and their similarities with myalgic encephalomyelitis/chronic fatigue syndrome: results of the retrospective CoLGEM study. Journal of Translational Medicine, v. 20, n. 1, p. 4–9, 2022. Disponível em: <https://doi.org/10.1186/s12967-022-03638-7>.
ROY, Devlina et al. Neurological and Neuropsychiatric Impacts of COVID-19 Pandemic. Canadian Journal of Neurological Sciences, v. 48, n. 1, p. 9–24, 2021.
SHAIK, Likhita e colab. COVID-19 and Sleep Disturbances: A Literature Review of Clinical Evidence. Medicina (Lithuania), v. 59, n. 5, p. 1–14, 2023.
TOKUMASU, Kazuki et al. Clinical Characteristics of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Diagnosed in Patients with. p. 1–9, 2022.
VOS, Theo et al. Estimated Global Proportions of Individuals with Persistent Fatigue, Cognitive, and Respiratory Symptom Clusters Following Symptomatic COVID-19 in 2020 and 2021. Jama, v. 328, n. 16, p. 1604–1615, 2022.
WEINSTOCK, Leonard B. et al. Restless legs syndrome is associated with long-COVID in women. Journal of Clinical Sleep Medicine, v. 18, n. 5, p. 1413–1418, 2022.
XU, Evan; XIE, Yan; AL-ALY, Ziyad. Long-term neurologic outcomes of COVID-19.
Nature Medicine, v. 28, n. 11, p. 2406–2415, 2022.
YASIN, Sedat et al. Post-acute sequelae of COVID-19 in young adults: Mental fatigue and decreased cognitive flexibility. Ideggyogyaszati Szemle, v. 76, n. 7–8, p. 261–269, 2023.
