Contraceptives Associated with the Risk of Thrombosis
DOI:
https://doi.org/10.55892/jrg.v7i15.1642Keywords:
Oral Contraceptives, Combined Contraceptive Pills, Thrombosis. Pharmaceutical CareAbstract
The use of contraceptives has grown globally, with more than 200 million users. In Brazil, hormonal, surgical, behavioral and barrier methods are recommended. Contraceptives containing estrogen can increase the risk of thrombosis, making it essential to raise awareness of these risks and adopt preventive measures. Thus, the main objective of this study was to address the association between the use of oral contraceptives and the risk of thrombosis. Through a systematic review of the literature, several studies that addressed this topic were analyzed. The results obtained demonstrate that the use of oral contraceptives, especially those with higher estrogen content and third-generation progestogens, significantly increases the risk of thrombotic events, such as deep vein thrombosis and pulmonary embolism. The review also explored the etiopathogenesis of thrombosis, highlighting the importance of Virchow's triad (endothelial injury, blood stasis and hypercoagulability) in this process. Furthermore, the different generations of contraceptives and their respective risks were discussed. It is concluded that the choice of contraceptive method should be individualized and carried out in conjunction with a health professional, considering the benefits and risks involved. Furthermore, health education and counseling on contraception are essential to ensure the safety and effectiveness of contraceptive methods.
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