Pharmaceutical interventions targeted pregnant women with syphilis: scoping review

Authors

DOI:

https://doi.org/10.55892/jrg.v7i15.1709

Keywords:

Syphilis, Congenital Syphilis, Pregnant Woman, Pharmaceutical Care, Public Health

Abstract

Introduction: According to estimates from the World Health Organization, approximately 1.5 million pregnant women worldwide are infected with syphilis annually, and half of these cases result in adverse outcomes for their children. Syphilis in pregnancy and congenital syphilis are significant public health issues, making it imperative to understand the extent of the disease at a local level. Objective: To conduct a literature review on existing evidence regarding pharmaceutical interventions for pregnant women with syphilis and congenital syphilis. Methodology: A scoping review guided by the PCC framework, where P = Population: Pregnant women with syphilis; C = Concept: Pharmaceutical Services/Pharmaceutical Care/Pharmacist-Provided Care; C = Context: Public health. The review covered the period from 2019 to 2024. Searches were conducted in databases, scientific article repositories, and grey literature. Inclusion and exclusion criteria were applied for article selection. Results and Discussion: Six articles met the inclusion criteria. The studies highlighted the severity of the disease and the pharmacist's role in addressing this condition. Conclusion: Measures aimed at improving care for pregnant women with syphilis are necessary, including the involvement of pharmacists, who are key professionals in disease screening and therapeutic follow-up.

Downloads

Download data is not yet available.

Author Biographies

Sâmela Gillian da Silva Bezerra, Federal University of Para

Graduada em Farmácia, Universidade Federal do Pará, Mestranda em Assistência Farmacêutica

Orenzio Soler, Federal University of Para

Graduado em Farmácia, Universidade Federal do Pará, Pós-Doutor em Políticas Públicas em Saúde

Carolina Heitmann Mares Azevedo Ribeiro, Federal University of Para

Graduada em Farmácia, Universidade Federal do Pará, Doutora em Farmácia (Fisiopatologia e Toxicologia)

Ana Cristina dos Santos Baetas Oliveira, Federal University of Para

Graduada em Farmácia, Universidade Federal do Pará, Doutora em Neurociência e Biologia Celular

References

ARKSEY H, O’Malley L. Scoping studies: towards a methodological framework. Int J Soc Res Meth. 2005;8(1):19-32. DOI: https://doi.org/10.1080/1364557032000119616

AROMATARIS, E.; MUNN, Z. JBI Manual for evidence synthesis. Joanna Briggs Institute, 2020. DOI: https://doi.org/10.46658/JBIMES-20-01

BARNES, Taylor; GIROTTO, Jennifer E.; Advocacy committee of the pediatric pharmacy association. The role of pediatric pharmacists in the prevention and treatment of congenital syphilis. The Journal of Pediatric Pharmacology and Therapeutics, v. 29, n. 4, p. 429–433, 2024. DOI: https://doi.org/10.5863/1551-6776-29.4.429.

BRASIL. Ministério da Saúde. Protocolo clínico e diretrizes terapêuticas para atenção integral às pessoas com infecções sexualmente transmissíveis (IST). Brasília: Ministério da Saúde, 2022. Disponível em: https://bvsms.saude.gov.br/bvs/publicacoes/protocolo_clinico_diretrizes_ist_2022.pdf

BRASIL. Ministério da Saúde. Relação Nacional de Medicamentos Essenciais: RENAME 2017. Brasília: Ministério da Saúde, 2017. Disponível em: https://www.gov.br/saude/pt-br/composicao/sectics/rename/rename-2017.pdf/view. Acesso em: 20 nov. 2024.

CENTRE FOR EVIDENCE-BASED MEDICINE. Nuffield Department of Primary Care Health Sciences. Radcliffe Primary Care Building, University of Oxford. Woodstock Road, Oxford. 2009. https://www.cebm.ox.ac.uk/resources/levels-of-evidence/oxford-centre-for-evidence-based-medicine-levels-of-evidence-march-2009

CRITICAL APPRAISAL SKILLS PROGRAMME (CASP). CASP checklist: 10 questions to help you make sense of qualitative research. Oxford, 2018. Disponível em: https://casp-uk.net/checklists/casp-qualitative-studies-checklist-fillable.pdf. Acesso em: 30 out. 2024.

FEU, Priscila Augusto; CARVALHO, Fabiano Lacerda; ANDRADE, Leonardo Guimaraes de. SÍFILIS CONGÊNITA: PERFIL EPIDEMIOLÓGICO E MEDIDAS DE ATENÇÃO FARMACÊUTICA. Revista Ibero-Americana de Humanidades, Ciências e Educação, [S. l.], v. 9, n. 10, p. 2372–2385, 2023. DOI: https://doi.org/10.51891/rease.v9i10.11771.

MARTINS, Gabrielle Ramos; ANDRADE, Leonardo Guimarães de. ATUAÇÃO DO FARMACÊUTICO NA PREVENÇÃO E ORIENTAÇÃO NO TRATAMENTO DA SÍFILIS CONGÊNITA. Revista Ibero-Americana de Humanidades, Ciências e Educação, [S. l.], v. 7, n. 10, p. 456–480, 2021. DOI: https://doi.org/10.51891/rease.v7i10.2587.

MONTEIRO, M. F. S. L.; SILVA, P. F. P. da; GONTIJO, Érica E. L.; SOUSA, T. R. de; JUREMA, H. C. Sífilis congênita e gestacional: eficácia dos medicamentos e atuação farmacêutica. Brazilian Journal of Health Review, [S. l.], v. 7, n. 3, p. e69468, 2024. DOI: https://doi.org/10.34119/bjhrv7n3-032.

MURAD, M. H. et al. New evidence pyramid. Evid Based Med, 2016, v. 21, n. 4, p. 125-127. DOI: 10.1136/ebmed-2016-110401.

OpenAI. (2023). GPT-3.5: Language Models and Chatbots. ChatGPT (openai.com). Há evidências de que intervenções farmacêuticas sejam efetivas para a adesão ao tratamento da sífilis em gestantes? Acesso em 10 de outubro de 2024: https://chatgpt.com/share/6709721c-6bf0-8000-adc6-8d78ba838ed7

PAGE, M. J.; MCKENZIE, J. E.; BOSSUYT, P. M.; BOUTRON, I.; HOFFMANN, T. C.; MULROW, C. D.; MOHER, D. (2021). The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. International journal of surgery, 2021, 88, 105906. Disponível em: https://www.bmj.com/content/bmj/372/bmj.n71.full.pdf. Acesso em: 20 nov. 2024.

PETERS, M.D.J. et al. Updated methodological guidance for the onduct of scoping reviews. JBI Evid Synth 2020;18(10):2119-26. DOI: https://doi.org/10.11124/JBIES-20-00167

PHAM, M.T. et al. A scoping review of scoping reviews: advancing the approach and enhancing the consistency. Res Synth Methods. 2014 Dec;5(4):371-85. DOI: https://doi.org/10.1002/jrsm.1123.

PORTO, Fagner dos Santos et al. Perfil sociodemográfico da sífilis (congênita e gestante) na microrregião de Almenara-MG e o papel do farmacêutico no enfrentamento da doença. ID Online Revista Multidisciplinar e de Psicologia, v. 14, n. 52, 2020. DOI: https://doi.org/10.14295/idonline.v14i52.2715.

SOLER, O.; BEZERRA, S. G. S; RIBEIRO, C. H. M. O.; OLIVEIRA, A. C. S. B. Intervenções farmacêuticas direcionadas à gestantes com sífilis: Revisão de escopo. https://doi.org/10.17605/OSF.IO/KZUS4. Disponível em: https://osf.io/kzus4/

TRICCO, A.C. et al. PRISMA Extension for Scoping Reviews PRISMA-ScR): checklist and explanation. Ann Intern Med, v.169, n. 7, p.:467-73, 2018. DOI: https://doi.org/10.7326/M18-0850

VELASCO, Clayton da Silva; ANDRADE, Leonardo Guimarães de. Sífilis: diagnóstico, tratamento e cuidado farmacêutico. Revista Ibero-Americana de Humanidades, Ciências e Educação, [S. l.], v. 8, n. 3, p. 1077–1088, 2022. DOI: https://doi.org/10.51891/rease.v8i3.4684.

WORLD HEALTH ORGANIZATION. WHO consolidated guidelines on drug-resistant tuberculosis treatment. Geneva: World Health Organization, 2019. Disponível em: https://iris.who.int/bitstream/handle/10665/277258/9789241565691-eng.pdf?sequence=5. Acesso em: 20 nov. 2024.

Published

2024-12-03

How to Cite

BEZERRA, S. G. da S.; SOLER, O.; RIBEIRO, C. H. M. A.; OLIVEIRA, A. C. dos S. B. Pharmaceutical interventions targeted pregnant women with syphilis: scoping review. JRG Journal of Academic Studies, Brasil, São Paulo, v. 7, n. 15, p. e151709, 2024. DOI: 10.55892/jrg.v7i15.1709. Disponível em: http://revistajrg.com/index.php/jrg/article/view/1709. Acesso em: 22 dec. 2024.

ARK