Analysis of the accuracy of indacianine green in robotic surgeries for sentinel lymph node identification associated with neoplasms

Authors

DOI:

https://doi.org/10.55892/jrg.v7i15.1745

Keywords:

Indocyanine green, Methylene Blue, Technetium, Robotic Surgical Procedures, Sentinel Lymph

Abstract

Technology advances every year, bringing innovations and knowledge that simplify daily life and increase safety in procedures. In medicine, robotic surgery is an excellent example of this progress, introducing innovations that enhance safety in complex procedures, such as oncological surgeries for the removal of cancerous tissues. In this context, the use of indocyanine green in robotic surgery stands out. This fluorescent substance enables the differentiation between areas with better blood perfusion and those with lower perfusion, facilitating the visualization of poorly vascularized cancerous nodules and allowing for the precise removal of compromised tissue. This review article discusses the use and advancements of indocyanine green in robotic surgery, focusing on its application in sentinel lymph node identification. Studies show promising results, with success rates exceeding those of traditional methods, suggesting a potential increase in the efficacy and safety of robotic surgery. The analysis of cases described in the literature, where this technique was utilized, illustrates the benefits of indocyanine green.

Downloads

Download data is not yet available.

Author Biographies

Victor Hugo Lima Dias, Afya Faculdade de Ciências Médicas de Jaboatão, PE, Brasil

Graduando(a) em Medicina pela AFYA Faculdade de Ciências Médicas de Jaboatão, PE.

João Alves da Costa Neto, Afya Faculdade de Ciências Médicas de Jaboatão

Graduando(a) em Medicina pela AFYA Faculdade de Ciências Médicas de Jaboatão, PE.

Bruno Ferreira Lopes, Afya Faculdade de Ciências Médicas de Jaboatão, PE, Brasil

Graduando(a) em Medicina pela AFYA Faculdade de Ciências Médicas de Jaboatão, PE.

Ana Paula Fernandes da Silva, Afya Faculdade de Ciências Médicas de Jaboatão, PE, Brasil

Doutora em Biologia aplicada à saúde – Universidade federal de Pernambuco (UFPE). Docente da AFYA Faculdade de Ciências Médicas de Jaboatão, PE

Adelmar Afonso de Amorim Junior, Afya Faculdade de Ciências Médicas de Jaboatão, PE, Brasil

Doutor em Anatomia dos Animais Domésticos e Silvestres – Universidade de São Paulo (USP). Docente da AFYA Faculdade de Ciências Médicas de Jaboatão, PE

References

AOUN, F. et al. Indocyanine green fluorescence-guided sentinel lymph node identification in urologic cancers: a systematic review and meta-analysis. Minerva urologica e nefrologica [The Italian journal of urology and nephrology], [s.l], v. 70, n. 4, ago./2018. Disponível em: <http://dx.doi.org/10.23736/S0393-2249.17.02932-0>.

HOW, J. et al. Comparing indocyanine green, technetium, and blue dye for sentinel lymph node mapping in endometrial cancer. Gynecologic oncology, [s.l], v. 137, n. 3, p. 436–442, jun./2015. Disponível em: <http://dx.doi.org/10.1016/j.ygyno.2015.04.004>.

BIZZARRI, N. et al. Sentinel lymph node mapping with indocyanine green in cervical cancer patients undergoing open radical hysterectomy: a single-institution series. Journal of cancer research and clinical oncology, [s.l], v. 147, n. 3, p. 649–659, set./2020. Disponível em: <http://dx.doi.org/10.1007/s00432-020-03393-6>.

PITSINIS, V. et al. Indocyanine green fluorescence mapping for sentinel lymph node biopsy in early breast cancer. Surgical oncology, [s.l], v. 24, n. 4, p. 375–379, dez./2015. Disponível em: <http://dx.doi.org/10.1016/j.suronc.2015.10.002>.

BUDA, A. et al. Sentinel lymph node mapping with near-infrared fluorescent imaging using indocyanine green: A new tool for laparoscopic platform in patients with endometrial and cervical cancer. Journal of minimally invasive gynecology, [s.l], v. 23, n. 2, p. 265–269, fev./2016. Disponível em: <http://dx.doi.org/10.1016/j.jmig.2015.09.022>.

LEE, E.-G. et al. Clinical application of multimodal sentinel lymph node mapping method in patients with breast cancer undergoing neoadjuvant chemotherapy: An interim analysis. Annals of surgical oncology, [s.l], v. 31, n. 8, p. 5141–5147, mai./2024. Disponível em: <http://dx.doi.org/10.1245/s10434-024-15317-6>.

CHAOWAWANIT, W. et al. Comparison between laparoscopic and robotic surgery for sentinel lymph node mapping in endometrial cancer using indocyanine green and near infra-red fluorescence imaging. Journal of obstetrics and gynaecology: the journal of the Institute of Obstetrics and Gynaecology, [s.l], v. 41, n. 4, p. 642–646, ago./2020. Disponível em: <http://dx.doi.org/10.1080/01443615.2020.1789953>.

ZENG, H.-C. et al. Detection of sentinel lymph nodes with near-infrared imaging in malignancies. Molecular imaging and biology: MIB: the official publication of the Academy of Molecular Imaging, [s.l], v. 21, n. 2, p. 219–227, jun./2019. Disponível em: <https://dx.doi.org/10.1007/s11307-018-1237-4>.

PÖLCHER, M. et al. Sentinel lymph node mapping with indocyanine green compared to blue dye tracer in gynecologic malignancies—A single center experience of 218 patients. Journal of surgical oncology, [s.l], v. 123, n. 4, p. 1092–1098, dez./2020. Disponível em: <http://dx.doi.org/10.1002/jso.26338>.

PARAISO MFR, TOMMASO F. Robot-assisted laparoscopy. UpToDate, [s.l], nov./2022. Disponível em: <https://www.uptodate.com/contents/robot-assisted-laparoscopy>.

MORRELL, A. L. G. et al. The history of robotic surgery and its evolution: when illusion becomes reality. Revista do Colegio Brasileiro de Cirurgioes, [s.l], v. 48, jan./2021. Disponível em: <http://dx.doi.org/10.1590/0100-6991e-20202798>.

HAERTEL, F. et al. The prognostic value of a liver function test using indocyanine green (ICG) clearance in patients with multiple organ dysfunction syndrome (MODS). Journal of clinical medicine, [s.l], v 13, n. 4, p. 1039, fev./2024. Disponível em: <http://dx.doi.org/10.3390/jcm13041039>.

SAMORANI, D. et al. The use of indocyanine green to detect sentinel nodes in breast cancer: A prospective study. European journal of surgical oncology: the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, [s.l], v. 41, n. 1, p. 64–70, jan./2015. Disponível em: <http://dx.doi.org/10.1016/j.ejso.2014.10.047>.

UJIIE, H. et al. Dose optimization of intravenous indocyanine green for malignant lung tumor localization. Journal of clinical medicine, [s.l], v. 13, n. 10, p. 2807, mai./2024. Disponível em: <http://dx.doi.org/10.3390/jcm13102807>.

WANG, H. et al. Indocyanine green-incorporating nanoparticles for cancer theranostics. Theranostics, [s.l], v. 8, n. 5, p. 1227–1242, fev./2018. Disponível em: <http://dx.doi.org/10.7150/thno.22872>.

CHOI, J. et al. Single camera-based dual-channel near-infrared fluorescence imaging system. Sensors (Basel, Switzerland), [s.l], v. 22, n. 24, p. 9758, dez./2022. Disponível em: <http://dx.doi.org/10.3390/s22249758>;

BARGON, C. A. et al. Sentinel lymph node mapping in breast cancer patients through fluorescent imaging using indocyanine green: The INFLUENCE trial. Annals of surgery, [s.l], v. 276, n. 5, p. 913–920, nov./2022. Disponível em: <http://dx.doi.org/10.1097/SLA.0000000000005633>.

XIE, D. et al. The application of indocyanine green in guiding prostate cancer treatment. Asian journal of urology, [s.l], v. 10, n. 1, p. 1–8, jan./2023. Disponível em: <http://dx.doi.org/10.1016/j.ajur.2021.07.004>.

TUMMERS, Q. R. J. G. et al. Real-time intraoperative detection of breast cancer using near-infrared fluorescence imaging and Methylene Blue. European journal of surgical oncology: the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, [s.l], v. 40, n. 7, p. 850–858, jul./2014. Disponível em: <http://dx.doi.org/10.1016/j.ejso.2014.02.225>.

SOMASHEKHAR, S. P. et al. Prospective study comparing clinical vs indocyanine green fluorescence–based assessment of line of transection in robotic rectal cancer surgery—Indian study. Indian journal of surgical oncology, [s.l], v. 11, n. 4, p. 642–648, set./2020. Disponível em: <http://dx.doi.org/10.1007/s13193-020-01207-2>.

Published

2024-12-09

How to Cite

DIAS, V. H. L.; COSTA NETO, J. A. da .; LOPES, B. F.; SILVA, A. P. F. da; AMORIM JUNIOR, A. A. de . Analysis of the accuracy of indacianine green in robotic surgeries for sentinel lymph node identification associated with neoplasms . JRG Journal of Academic Studies, Brasil, São Paulo, v. 7, n. 15, p. e151745, 2024. DOI: 10.55892/jrg.v7i15.1745. Disponível em: http://revistajrg.com/index.php/jrg/article/view/1745. Acesso em: 9 jan. 2025.

ARK