Nutritional Screening and Diagnostic Instruments in Cancer Patients: An Integrative and Contemporary Approach.
DOI:
https://doi.org/10.55892/jrg.v8i18.1817Keywords:
Nutritional assessment, Nutritional Status, Protein-Calorie Malnutrition, Neoplasms, Hospital Nutrition ServiceAbstract
Cancer represents a complex condition with significant global prevalence, affecting approximately 1 in 5 people. Malnutrition, closely associated with the disease, can vary between 20% and 80% of cases, directly impacting the therapeutic outcomes and quality of life of patients. The present study aims to analyze and integrate contemporary instruments for nutritional screening and diagnosis in cancer patients, aiming to understand their characteristics, applicability and potential contributions to nutritional management. This is an integrative bibliographic review carried out between November 2023 and October 2024. Databases such as SciELO, Pubmed, and Lilacs were used, with inclusion criteria for studies published between 2014-2024, involving adults and older adults with cancer, in Portuguese, English, and Spanish. Instruments such as NRS-2002, Graz Malnutrition Screening (GMS), AND-ASPEN and GLIM were identified, each with specific characteristics of nutritional screening and diagnosis. The MSG showed greater sensitivity compared to the NRS-2002, while the GLIM method proved to be robust for diagnosing moderate and severe malnutrition. The results highlighted the complexity of oncological nutritional assessment, highlighting the importance of multidisciplinary approaches and standardized instruments for early identification of nutritional risks. It is recommended to implement integrated protocols that combine multiple instruments, potentially reducing morbidity and mortality and improving the quality of life of cancer patients.
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ALIKIAII, B. et al. Evaluation of the effectiveness of the Nutritional Risk Screening System 2002 (NRS-2002) in COVID-19 patients admitted to the intensive care unit. International Journal of Clinical Practice, v. 75, n. 12, p. e14934, 2021.
ARENDS, J. et al. ESPEN guidelines on nutrition in cancer patients. Clinical Nutrition, v. 36, n. 1, p. 11-48, 2017.
BARBOSA, A. P. et al. Comparação entre diferentes métodos de diagnóstico de desnutrição em pacientes oncológicos. Revista Brasileira de Cancerologia, v. 65, n. 3, p. e-1234, 2019.
BAUER, J.; CAPRA, S.; FERGUSON, M. Use of the scored patient-generated subjective global assessment (PG-SGA) as a nutrition assessment tool in patients with cancer. European Journal of Clinical Nutrition, v. 56, n. 8, p. 779-785, ago. 2002.
BEZERRA, J, D, et al. Aplicação de instrumentos de triagem nutricional em hospital geral: um estudo comparativo. Revista Ciência & Saúde, Porto Alegre, v. 5, n. 1, p. 9-15, jan./jun. 2012
BRAY, F. et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, v. 74, n. 3, p. 229-263, 2024.
CARLOS, M. L. et al. Triagem nutricional em pacientes oncológicos. Ministério da Saúde, Brasília, 2024.
CEDERHOLM, T; et al. GLIM criteria for the diagnosis of malnutrition - A consensus report from the global clinical nutrition community. Clinical nutrition, 38(1), 1–9. 2019. https://doi.org/10.1016/j.clnu.2018.08.002
CUNHA, M. S. Avaliação Subjetiva Global Produzida Pelo Paciente versão reduzida: validação de um ponto de corte preditivo de sobrevida para pacientes em cuidados paliativos oncológicos. Dissertação de Mestrado, Instituto Nacional de Câncer, Rio de Janeiro, 2024.
DETSKY, A, S, et al. What is the subjective global assessment of nutritional status? J Parenter Enteral Nutr. 1987; 11:8-13.
FAXÉN-IRVING, G., LUIKING, Y., GRÖNSTEDT, H., FRANZÉN, E., SEIGER, Å., VIKSTRÖM, S., WIMO, A., BOSTRÖM, A. M., & CEDERHOLM, T. Do Malnutrition, Sarcopenia and Frailty Overlap in Nursing-Home Residents?. The Journal of frailty & aging, 10(1), 17–21. 2021. https://doi.org/10.14283/jfa.2020.45
FEARON, K. C.; GLASS, D. J.; GUTTRIDGE, D. C. Cancer cachexia: mediators, signaling, and metabolic pathways. Cell Metabolism, v. 16, n. 2, p. 153-166, 2012. Disponível em: https://doi.org/10.1016/j.cmet.2012.06.011. Acesso em: 12 set. 2024.
GONZALEZ, M. C. et al. Nutritional status and body composition in cancer patients during chemotherapy. Supportive Care in Cancer, v. 22, n. 8, p. 2109-2116, 2014.
GONZALEZ, M.C.; et al. Validação da versão em português da ASG-PPP. Rev Bras Nutr Clin; 25 (2): 102-8. 2010.
GULSOY, K. Y.; ORHAN, S. The Relationship between Mortality and the Modified Nutrition Risk in Critically Ill (mNUTRIC) and Nutritional Risk Screening 2002 (NRS-2002) Scores in the Intensive Care Unit. Journal of the College of Physicians and Surgeons--Pakistan: JCPSP, v. 32, n. 7, p. 848-854, 2022.
INSTITUTO NACIONAL DE CÂNCER JOSÉ ALENCAR GOMES DA SILVA. ABC do câncer: abordagens básicas para o controle do câncer. Instituto Nacional de Câncer José Alencar Gomes da Silva. Rio de Janeiro–RJ. 3°Ed, 2017. 108 p.
INSTITUTO NACIONAL DE CÂNCER JOSÉ ALENCAR GOMES DA SILVA. Estimativa de incidência de Câncer no Brasil - Biênio 2018-2019. Vol. 1, Inca. 2018. 124 p.
INSTITUTO NACIONAL DE CÂNCER JOSÉ ALENCAR GOMES DA SILVA. Estimativa de 2023: Incidência de câncer no Brasil. Rio de Janeiro: INCA; 2023. [Acesso em 24/04/2024] disponível em: www.gov.br/inca/pt-br/assuntos/cancer/numeros/estimativa
JENSEN, G. L. et al. GLIM criteria for the diagnosis of malnutrition – A consensus report from the global clinical nutrition community. Clinical Nutrition, v. 38, n. 1, p. 1-9, 2019.
KONDRUP, J. et al. ESPEN Guidelines for Nutrition Screening 2002. Clinical Nutrition, v. 22, n. 4, p. 415-421, 2003.
KONDRUP, J. et al. Nutritional risk screening (NRS-2002): a new method based on an analysis of controlled clinical trials. Clinical Nutrition, v. 22, n. 3, p. 321-336, 2002.
LATY, B, C, et al. Prevalência e prognóstico de desnutrição determinados pelo critério GLIM. BRASPEN J.; 35 (1): 49-55. 2020.
LEW, C. C. H. et al. Nutritional Risk Screening (NRS 2002) as a Predictor of Postoperative Outcomes: A Systematic Review. Clinical Nutrition, v. 36, n. 6, p. 1549-1558, 2017.
LIMA, E. M. B. et al. Agreement between Graz Malnutrition Screening (GMS) with subjective nutritional assessment instruments in hospitalized patients. Nutrición Hospitalaria, v. 35, n. 5, p. 1138-1144, 2018.
LIMA, G, E, S & SILVA, B, Y, C. Ferramentas de triagem nutricional: um estudo comparativo. BRASPEN J 2017; 32 (1): 20-4
LYRA, E; ALIGLERI, T; BATISTON, L; HENCKEL, V. Estado nutricional e tempo de jejum pré-operatório de pacientes oncológicos submetidos à cirurgia. R. Assoc. bras. Nutr; 14 (1): 1-15. 2023.
MALONE, A.; HAMILTON, C. The Academy of Nutrition and Dietetics/The American Society for Parenteral and Enteral Nutrition Consensus Malnutrition Characteristics: Application in Practice. Nutrition in Clinical Practice, v. 28, n. 6, p. 639-650, 2013.
NASCIMENTO, N, C, et al. Comparação de métodos de detecção da desnutrição no ambiente hospitalar. Nutr. clín. diet. hosp; 37(1): 34-40. 2017.
OTTERY F. D. Definition of standardized nutritional assessment and interventional pathways in oncology. Nutrition, 12(1 Suppl), S15–S19. 1996. https://doi.org/10.1016/0899-9007(96)90011-8
PEIXOTO, M.I., DOURADO, K.F., ANDRADE, M.I., SILVA, T.D., FRANÇA, A.K., ALMEIDA, H.R., VASCONCELOS, A.A., & MELO, L.S. Comparação entre diferentes métodos de triagem nutricional em pacientes oncológicos ambulatoriais. 2017.
PINHO, N. B. et al. Prevalência de desnutrição em pacientes hospitalizados com câncer: um estudo multicêntrico. Clinical Nutrition, v. 40, n. 5, p. 2345-2353, 2021.
PROCKMANN, S; RUSCHEL, F, A, H; GONÇALVES, F, M; KUNRADI, V, F, G; KUERTEN, S, R. Evaluation of diet acceptance by patients with hematological cancer during chemotherapeutic treatment. Nutr Hosp. 2015 Aug 1;32(2):779-84
ROLLER, R. E. et al. The Graz Malnutrition Screening (GMS): a new hospital screening tool for malnutrition. British Journal of Nutrition, 2016.
ROLLER, R. E. et al. Validity of the Graz Malnutrition Screening as an indicator of nutritional status in hospitalized patients. Nutrition in Clinical Practice, v. 37, n. 2, p. 465-472, 2022.
ROSA, G.M., HOFSTÄTTER, K., NICOLA, C., RIBOLI, J.A., & SECCON, T.M. Impactos da pandemia da COVID-19 no meio ambiente: uma breve análise. Concilium. 2022.
SANTOS, A. L. et al. Diagnóstico Nutricional: Estratégias e Aplicações Clínicas. Revista Brasileira de Nutrição Clínica, v. 36, n. 2, p. 145-156, 2021.
SILVA SANTOS, et al. Comparação da especificidade e sensibilidade entre os métodos de triagem nutricional Nutritional Risk Screening 2002 e Graz Malnutrition Screening em pacientes oncológicos hospitalizados. Nutr. clín. diet. hosp. 2019; 39(2): 84-89.
SILVA, F. et al. Critérios de desnutrição pela GLIM: associação com mortalidade em pacientes em unidades de terapia intensiva. Semantics Scholar, 2023. Disponível em: <https://www.semanticscholar.org/paper/6fcbfc96fd86be367cdb1e63886deed8a5a8e937>. Acesso em: 23 dez. 2024.
SINGER, P. et al. Nutritional Risk Screening 2002 as a Predictor of Outcome in Critically Ill Patients. Nutrition, v. 35, p. 134-141, 2019.
TISDALE, M. J. Mechanisms of cancer cachexia. Physiological Reviews, v. 89, n. 2, p. 381-410, 2009. Disponível em: https://doi.org/10.1152/physrev.00016.2008. Acesso em: 12 set. 2024.
VIGANO, A. L. et al. The abridged patient-generated subjective global assessment is a useful tool for early detection and characterization of cancer cachexia. Journal of the Academy of Nutrition and Dietetics, v. 114, n. 7, p. 1088-1098, 2014.
WHITE, J. V. et al. Consensus statement: Academy of Nutrition and Dietetics and American Society for Parenteral and Enteral Nutrition: characteristics recommended for the identification and documentation of adult malnutrition (undernutrition). Journal of Parenteral and Enteral Nutrition, v. 36, n. 3, p. 275-283, 2012. Disponível em: https://doi.org/10.1177/0148607112440285. Acesso em: 12 set. 2024.
WIEGERT, E. V. M. et al. Desempenho prognóstico da Avaliação Subjetiva Global Produzida pelo Paciente em pacientes oncológicos. Revista Brasileira de Cancerologia, v. 65, n. 3, p. 315-324, 2019.
ZHANG, L.; LU, Y.; FANG, J. Nutritional assessment and intervention in gastrointestinal cancer patients. Nutrition and Cancer, v. 65, n. 8, p. 1138-1145, 2013.