Benefits of using medicinal plants as therapy for leishmaniasis: a narrative review
DOI:
https://doi.org/10.55892/jrg.v8i18.1768Keywords:
Leishmaniose, Plantas medicinais, Fitoterapia, Terapias complementaresAbstract
Objective: To address the benefits of using medicinal plants to treat leishmaniasis in humans, providing low cost and reducing resistance to chemotherapy. Methodology: This is a narrative review conducted in the Virtual Health Library (VHL), Scientific Electronic Library Online (SciELO), Public Medline (MEDLINE), and Latin American and Caribbean Literature on Health Sciences (LILACS). In addition, Google Scholar was used in isolation to complement the search. Results: The review consisted of eight articles. Several medicinal plants have been studied for the treatment of leishmaniasis. Bidens pilosa and Punica granatum have shown efficacy against the parasite, but Bidens pilosa also has immunomodulatory properties that may affect disease control. S. lucocarpum, A. glabra, and S. striata have also demonstrated leishmanicidal activity. Zerumbone, present in natural foods, has several biomedical properties. Jatropha multifida has shown antileishmanial activity and inhibition of bacterial growth. Studies with other plants, such as Carthamus tinctorius, Pimpinella anisum, Cuminum cyminum, Cinnamomum verum and Alhagi persarum, have shown efficacy against the parasite. These plants have potential as therapeutic alternatives for leishmaniasis; however, further research is needed to confirm their efficacy and safety. Final considerations: These studies highlighted the potential of several plants and plant extracts as sources of compounds with antiparasitic activity. Although further research and clinical studies are still needed to evaluate their efficacy and safety, these findings pave the way for the development of new therapies and drugs against leishmaniasis.
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